Chylothorax in Henoch‐Schonlein purpura: A case report and review of the literature
Identifieur interne : 008489 ( Main/Exploration ); précédent : 008488; suivant : 008490Chylothorax in Henoch‐Schonlein purpura: A case report and review of the literature
Auteurs : Bryan D. Cogar [États-Unis] ; Ted D. Groshong [États-Unis] ; Brian K. Turpin [États-Unis] ; Jesus R. Guajardo [États-Unis]Source :
- Pediatric Pulmonology [ 8755-6863 ] ; 2005-06.
Abstract
Henoch‐Schonlein purpura (HSP) is the most common acute vasculitis in the pediatric population, with an incidence of 10–14 per 100,000. The classic presentation of this disorder includes erythematous papules followed by palpable purpura in the lower extremities, trunk, and face, arthralgia or arthritis, abdominal pain, gastrointestinal bleeding, and nephritis. While renal abnormalities in HSP are common, the classic pulmonary manifestations, such as hemorrhage and pneumonitis, are thought to be infrequent. Subclinical pulmonary manifestations, including diffusion defects and radiographic anomalies, seem to be quite frequent in patients with HSP but are not commonly reported. Other respiratory manifestations include pleural effusion and chylothorax, but these are rarely mentioned in the literature. Chylothorax was only reported once in an adult patient with HSP in whom the mechanism of formation was demonstrated to be secondary to transdiaphragmatic passage of chylous fluid from the peritoneal cavity. Here we describe an 8‐year‐old girl with HSP, nephrotic syndrome, and chylothorax, and we report the results of a review of the literature regarding respiratory complications in HSP. The present case is the first pediatric patient reported with HSP and chylothorax. The therapeutic measures utilized were effective in resolving her edema, ascites, and chylothorax, and we advocate the use of these measures as first‐line therapy in future patients with similar complications from HSP. © 2005 Wiley‐Liss, Inc.
Url:
DOI: 10.1002/ppul.20203
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The classic presentation of this disorder includes erythematous papules followed by palpable purpura in the lower extremities, trunk, and face, arthralgia or arthritis, abdominal pain, gastrointestinal bleeding, and nephritis. While renal abnormalities in HSP are common, the classic pulmonary manifestations, such as hemorrhage and pneumonitis, are thought to be infrequent. Subclinical pulmonary manifestations, including diffusion defects and radiographic anomalies, seem to be quite frequent in patients with HSP but are not commonly reported. Other respiratory manifestations include pleural effusion and chylothorax, but these are rarely mentioned in the literature. Chylothorax was only reported once in an adult patient with HSP in whom the mechanism of formation was demonstrated to be secondary to transdiaphragmatic passage of chylous fluid from the peritoneal cavity. Here we describe an 8‐year‐old girl with HSP, nephrotic syndrome, and chylothorax, and we report the results of a review of the literature regarding respiratory complications in HSP. The present case is the first pediatric patient reported with HSP and chylothorax. The therapeutic measures utilized were effective in resolving her edema, ascites, and chylothorax, and we advocate the use of these measures as first‐line therapy in future patients with similar complications from HSP. © 2005 Wiley‐Liss, Inc.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Missouri (État)</li></region></list><tree><country name="États-Unis"><region name="Missouri (État)"><name sortKey="Cogar, Bryan D" sort="Cogar, Bryan D" uniqKey="Cogar B" first="Bryan D." last="Cogar">Bryan D. Cogar</name></region><name sortKey="Groshong, Ted D" sort="Groshong, Ted D" uniqKey="Groshong T" first="Ted D." last="Groshong">Ted D. 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